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Paper | Regular issue | Vol 36, No. 1, 1993, pp.101-105
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6168
■ The Synthesis of Three Isomers of the Food Carcinogen IQ

Erik Ronne and Spiros Grivas*

*Department of Chemistry, Swedish University of Agricultural Sciences, P.O.Box 7015, SE-750 07 Uppsala, Sweden

Abstract

2-Amino-3-methyl-3H-imidazo[4,5-h]quinoline, 2-amino-3-methyl-3H-imidazo[4,5-f]isoquinoline and 2-amino-3-methyl-3H-imidazo[4,5-h]isoquinoline were synthesized from 7-methoxyquinoline, 6- and 7-methoxyisoquinolines in 21-28% overall yields.