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Communication | Regular issue | Vol 34, No. 10, 1992, pp.1877-1884
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6140
The Chemistry of 1-Hydroxyindole Derivatives: Nucleophilic Substitution Reactions on Indole Nucleus

Masanori Somei,* Toshiya Kawasaki, Yoshikazu Fukui, Fumio Yamada, Tetsuya Kobayashi, Harumi Aoyama, and Daisuke Shinmyo

*Faculty of Pharmaceutical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa 920, Japan


Nucleophilic substitution reactions were newly found to occur generally in the chemistry of 1-hydroxyindole derivatives. Its application to the synthesis of a phytoalexin, brassicanal A, is reported.