Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 36, No. 1, 1993, pp.55-62
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6104
Nucleophilicity of 3-Alkyl-2-(N-cyanoimino)thiazolidines: Methylated Products and Their Reactivity

Chuzo Iwata,* Tetsuya Kawakami, Michitaro Fujimoto, Yumi Nakamoto, and Tetsuaki Tanaka

*Faculty of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Toyonaka, Osaka 560-0043, Japan


3-Alkyl-2-(N-cyanoimino)thiazolidines were methylated mainly at the nitrile nitrogen atom with trimethyloxonium tetrafluoroborate (Me3O·BF4). The reaction of the methylated products, the nitrilium salts, with sodio diethyl malonate was described.