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Paper | Regular issue | Vol 34, No. 9, 1992, pp.1711-1720
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6058
Fused 1,2,4-Triazole Heterocycles. I. Synthesis of Novel [1,2,4]Triazolo[5’,1’:2,3][1,3]thiazino[6,5-b]quinolines.

Ferenc Kóródi,* Zoltán Cziáky, and Zoltán Szabó

*Alkaloida Chemical Company Ltd., H-4440 Tiszavasvári, Hungary

Abstract

Derivatives of a new heterocyclic ring system of [1,2,4]triazolo[5’,1’:2,3][1,3]thiazino[6,5-b]quinolines (4, 5, 6, 7 and 8) have been synthesised by the reaction of 2-chloroquinoline-3-carbaldehyde derivatives (1 and 2) with 1,2,4-triazole-5-thiols (3), and subsequent transformations of the hydroxy group of 11-hydroxy[1,2,4]triazolo[5’,1’:2,3][1,3]thiazino[6,5-b]quinoline (4a).