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Paper | Regular issue | Vol 34, No. 6, 1992, pp.1169-1175
Published online, 1st January, 1970
DOI: 10.3987/COM-92-6009
Synthesis of Some 5-Substituted Indoles

Youhua Yang, Arnold R. Martin,* David L. Nelson, and John Regan

*Department of Pharmaceutical Sciences, College of Pharmacy, University of Arizona, Tucson, AZ 85721, U.S.A.


A halogen-metal exchange strategy was employed to prepare several 5-substituted indoles from 5-bromoindole. Additional derivatives were elaborated from the formyl, acetyl, thiomethyl, boronic acid and trimethylstannyl analogues thus prepared.