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Communication | Regular issue | Vol 34, No. 5, 1992, pp.891-894
Published online, 1st January, 1970
DOI: 10.3987/COM-92-5989
Synthesis of 6-Phenylaminofuro[2,3-d]pyrimidine-2,4(1H,3H)-diones from Barbiturylbenzylidenes and Isonitriles

José Daniel Figueroa-Villar,* Carisa Lopes Carneiro, and Elizabete Rangel Cruz

*Seção de Química, Instituto Militar de Engenharia, Pç Gal. Tibúrcio 80 22290, Rio de Janeiro, RJ, Brazil


Barbiturylbenzylidenes, prepared by Perkin condensation of aromatic aldehydes with 1,3-dimethylbarbituric acid, react with phenylisonitrile to yield four 5-aryl-6-phenylamino-1,3-dimethylfuro[2,3-d]pyrimidine-2,4(1H,3H)-diones.