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Paper | Regular issue | Vol 34, No. 5, 1992, pp.937-942
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5947
Regioselective O-Demethylation of Bisbenzylisoquinoline Alkaloids

Jun-ichi Kunitomo,* Megumi Oshikata, Michinori Akasu, and Hisashi Ishii

*Faculty of Pharmaceutical Sciences, Mukogawa Women’s University, 11-68 Koshien Kyuban-cho, Nishinomiya, Hyogo, 663, Japan


The cleavage of methyl ethers of several bisbenzylisoquinoline alkaloids was studied and regioselective O-demethylation was observed.