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Paper | Regular issue | Vol 32, No. 11, 1991, pp.2127-2137
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5816
A New Synthetic Approximation to Thiazoles with a Versatile Persubstitution and/or Perfunctionalization

Carlos Alvarez-Ibarra,* Rosario Asperilla, César de Dios-Corredor, Elena Martínez-Santos, and Mario Luz Quiroga

*Departamento de Química Orgánica, Facultad de Química, Universidad Complutense de Madridas, Ciudad Universitaria, E-28040 Madrid, Spain


A new synthetic approach to 2-alkyl-, 2-aryl-, and 2-N-alkylaminothiazoles has been carried out. This strategy is based on the high versatility of synthons derived from 2-methylthiothiazoles.