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Paper | Regular issue | Vol 34, No. 4, 1992, pp.689-698
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5791
Two New Withanolides from Withania somnifera

Atta-ur-Rahman,* S. Arshad Jamal, and M.Iqbal Choudhary*

*H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan


Two new withanolides, sominone (1α,3β,27-trihydroxy-22(R)-witha-5,24-dienolide) (1) and sominolide (4β,27-dihydroxy-14α,15α-epoxy-1-oxo-22-(R)-witha-2,24-dienolide) (2) were isolated from the herbs of Withania somnifera Dun. (Solanaceae). The elucidation of their structures is based on extensive spectroscopic studies.