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Paper | Regular issue | Vol 32, No. 7, 1991, pp.1351-1356
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5750
A Convenient Synthesis of Adenosine 3’,5’-Cyclic Phosphate (cAMP) Benzyl and Methyl Triesters

Shigehiro Kataoka,* Riichiro Uchida, and Nobuyuki Yamaji

*Research and Development Division, Kikkoman Corporation, 399 Noda, Noda-shi, Chiba 278, Japan

Abstract

The benzyl and methyl triesters of cAMP were synthesized from cAMP tri-n-butylammonium salt by alkylation with alkyl halides in the presence of Na2CO3 in dimethylacetamide (DMA).