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Paper | Regular issue | Vol 32, No. 7, 1991, pp.1341-1350
Published online, 1st January, 1970
DOI: 10.3987/COM-91-5748
Synthetic Studies on Indole Alkaloids. IV. Studies on N-Phenylsulfonyl-2-methylindoles on Intramolecular Cyclizations

Mario Rubiralta,* Anna Diez, Cristina Vila, Yves Troin, and David Miguel

*Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Av. de Joan XXIII, s/n, 08028 Barcelona, Spain


The synthesis of 1-(2-hydroxyethyl)-2-[2-methyl-N-(phenylsulfonyl)-2-indolyl]-4-piperidone ethylene ketal (4) by two alternative ways and the study of its intramolecular cyclization using potassium tert-butoxide are reported.