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Paper | Regular issue | Vol 31, No. 12, 1990, pp.2139-2145
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5541
Heterocyclizations of Thiosemicarbazones with α-Chloroacetyl Chloride

Shigeru Kabashima, Yasuhiro Tomita, Tadashi Ohkawara, Tetsuo Yamasaki, and Mitsuru Furukawa*

*Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-hon-machi, Kumamoto 862-0973, Japan


4-substituted thiosemicarbazones were allowed to react with α-chloroacetyl chloride to give two types of 1,3-thiazolin-4-ones which arose from the different cyclization depending on the substituents.