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Paper | Regular issue | Vol 31, No. 9, 1990, pp.1721-1725
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5523
Practical Synthesis of (S)-1-Octyn-3-ol: A Key Intermediate for the Prostaglandin Synthesis

Seiichi Takano,* Takumichi Sugihara, and Kunio Ogasawara

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


Practical synthesis of (S)-octyn-3-ol is devised starting from (2S,3S)-2,3-O-isopropylidenedioxyoctanol readily accessible from diethyl (L)-tartrate.