Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 31, No. 11, 1990, pp.1983-1996
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5520
Fused Imidazophenothiazines: Synthesis of 2-Methyl-3-phenyl-6H-imidzo[4,5-c]phenothiazine

Pilar López-Alvarado, Carmen Avendaño,* Mercedes T. Grande, and J. Carlos Menéndez

*Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense de Madrid, Ciudad Universitaria, 28040 Madrid, Spain


A new and reliable procedure for the multigram-scale preparation of 2-methyl-1-phenyl-5-phenylaminobenzimidazole (6) is reported. Bernthsen thionation of 6 leads to 2-methyl-3-phenyl-6H-imidazo[4,5-c]phenothiazine (9), whose structure was established through a detailed mono- and bidimensional 1H-nmr and 13C-nmr spectroscopic study of model compounds.