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Paper | Regular issue | Vol 31, No. 9, 1990, pp.1641-1646
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5472
Synthesis and X-Ray Analysis of 1-Benzyl-6-chlorouracil

Ichiro Ishikawa, Tsuneo Itoh, Raphael G. Melik-Ohanjanian, Hiroaki Takayanagi, Yoshihisa Nizuno, Haruo Ogura*, and Norio Kawahara

*School of Pharmaceutical Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan


1-Benzyl-6-chlorouracil (3) was prepared by benzylation of 6-chlorouracil (2) which was obtained by alkaline hydrolysis of 2,4,6-trichloropyrimidine (1).