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Paper | Regular issue | Vol 31, No. 8, 1990, pp.1497-1504
Published online, 1st January, 1970
DOI: 10.3987/COM-90-5434
Synthesis of Some Conformationally Restricted Analogs of Serotonin

John E. Macor* and Kevin Ryan

*Department of Medical Chemistry, Central Research Division, Pfizer Inc., Groton, Connecticut 06355, U.S.A.


3-(2-Aminocycloalkyl)-5-methoxyindoles (3) have been synthesiezed via a three setp procedure starting with 5-methoxyindole. These molecules represent conformationally restricted analogs of serotonin.