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Paper | Special issue | Vol 30, No. 2, 1990, pp.885-896
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S77
2-Oxotetrahydro-1,3-oxazine: A Useful Interamediate for the Preparation of Tetrahydropyridine, Indolizidine, and Quinolizidine Skeletons

Takushi Kurihara,* Yoshitaka Matsubara, Hirotaka Osaki, Sinya Harusawa, and Ryuji Yoneda

*Faculty of Pharmaceutical Science, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan

Abstract

Conversion of 2-oxotetrahydro-1,3-oxazines into tetrahydropyridines was applied to the synthesis of indolizidine and quinolizidine alkaloids.