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Communication | Special issue | Vol 30, No. 1, 1990, pp.223-226
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S7
4,5,6,7-Tetrahydroisobenzofuran-5-one as a Versatile Building Block Leading to the Basic Skeleton of Naturally Occurring Fused Furans

Yasuchika Yamaguchi, Noriaki Tatsuta, Seizo Soejima, Kenji Hayakawa, and Ken Kanematsu*

*Faculty of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan


4,5,6,7-Tetrahydroisobenzofuran-5-one as a building block has been prepared via the furan ring transfer (FRT) reactions utilizing an allene intramolecular Diels-Alder reaction, which provides a single route to the construction of the tricyclic furans.