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Paper | Special issue | Vol 30, No. 1, 1990, pp.561-566
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S57
Stereoselective Formal Synthesis of (±)-Monomorine I from 6-Methyl-2-piperidinone

Tatsuo Nagasaka,* Hiroki Kato, Hideki Hayashi, Masako Shioda, Hiromi Hikasa, and Fumiko Hamagichi

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


The stereoselective formal synthesis of (±)-monomorine I from 6-methyl-2-piperidinone was achieved. A general method for the synthesis of ω-alkylated lactams is also described.