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Communication | Special issue | Vol 30, No. 1, 1990, pp.271-273
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S29
The Firat Synthesis of Mutagenic Trp-P-1 via the Electrocyclic Reaction of 1-Azahexa-1,3,5-triene System

Satoshi Hibino,* Eiichi Sugino, Naoki Sgura, Yohko Shintani, and Kohichi Sato

*Graduate School of Pharmacy and Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Hiroshima 729-0292, Japan


The first total synthesis of Trp-P-1 (1) has been completed by the thermal electrocyclic reaction of 1-azahexa-1,3,5-triene system (3).