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Communication | Special issue | Vol 30, No. 1, 1990, pp.205-209
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S2
A New Bisbenzylisoquinoline Alkaloid from Phaenthus vietnamensis and Its Antibacterial Activity

Petr Sedmera, Nguyen Thi Nghia, Ivo Válka, André Cavé, Diego Cortés, and Vilím Simánek*

*Institute of Medical Chemistry, Palacky University, 3, Hnevotínská, 775 15 Olomouc, Czech Republic


A new bisbenzylisoquinoline alkaloid (-)-(1S,1’R)-O,O’-dimethylgrisabine (1) was isolated the leaves of Phaeanthus vietnamensis Ban. Its structure was determined on the basis of the extensive 2-D and 1-D nmr long-range heteronuclear correlations. Its antibacterial activity is also described.