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Communication | Special issue | Vol 30, No. 1, 1990, pp.231-235
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S12
Syntheses of Pyrido[2,3-d]pyrimidine Nucleosides via 6-Allylaminouridines from 6,5’-Anhydroridine Derivative and Allyamines

Tsuneo Itoh,* Ichiro Ishikawa, Yasuo Tomii, Yoshihisa Mizuno, Haruo Ogura, and Norio Kawahara

*School of Pharmaceutical Sciences, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan


Pyrido[2,3-d]pyrimidine nucleosides were readily synthesized by treatment of 2’,3’-O-isopropylidene-6-allylaminouridines, which were derived from 6,5’-anhydro-2’,3’-O-isopropylidene-6-hydroxyuridine and allylamines with palladium(II) acetate.