Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Special issue | Vol 30, No. 2, 1990, pp.1141-1153
Published online, 1st January, 1970
DOI: 10.3987/COM-89-S113
Nucleotides, XXXIII: Synthesis and Properties of Inosinate Trimer I2’p5’I2’p5’I and Inosinate Tetramer I2’p5’I2’p5’I2’p5’I

Ramamurthy Charubana and Wolfgang Pfleiderer*

*Fakultät für Chemie, Universität Konstanz, Posttach 5560, D-7750 Konstantz, Germany

Abstract

The chemical synthesis of 2’-5’ inosinate trimer and tetramer was achieved by the phosphotriester method using the 2-(p-nitrophenyl)ethyl group for phosphate protection. The sugar hydroxyl groups have either been protected by the (tert-butyl)-dimethylsilyl or the benzoyl group. Final deprotection to the unblocked oligomers was achieved in over 85% yield. The inosinate oligomers show some antiviral activity against TMV.