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Paper | Regular issue | Vol 29, No. 11, 1989, pp.2157-2166
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5144
Synthesis of (±)-Solenopsin A and (±)-Isosolenopsin A from 6-Methyl-2-piperidinone

Tatsuo Nagasaka,* Hideki Hayashi, Masaki Kumakawa, Masako Sakamoto, Masami Mizuno, and Fumiko Hamaguchi

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

(±)-Solenopsin A and (±)-isosolenopsin A were synthesized as a mixture in six steps from 6-methyl-2-piperidinone and they could be easily separated from each other as isomers.