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Paper | Regular issue | Vol 31, No. 1, 1990, pp.87-95
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5127
Synthesis of an Aminoisoxazolidine Substituted Quinolone Acid

Kyoung Soon Kim*

*Cancer and Infectious Diseases Research, The Upjohn Company, Kalamazoo, Michigan 49001, U.S.A.

Abstract

New heterocycle aminoisoxazolidine 7 and tetrafluorobenzoic acid are synthesized for the synthesis of a quinolone antibacterial agent. The synthesis of a chiral aminoisoxazolidines substituted quinolone acid, U-82662A, is described.