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Paper | Regular issue | Vol 29, No. 10, 1989, pp.1983-1991
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5097
Regioselective Synthesis of 2- and 3-Acylpyrroles by Reaction of β-Aminoenones with α-Aminoketone Hydrochloride

Angel Alberola,* José M. Andrés, Alfonso González, Rafael Pedrosa, and Martina Vicente

*Deparamento de Química Orgánica, Facultad de Ciencias, Universidad de Valladolid, 47005 Valladolid, Spain

Abstract

A high regioselective synthesis, with good to excellent yields, of 2- and 3-acylpyrroles from β-aminoenones and α-aminoketones is described. The formation of 2-acylpyrroles or their 3-acylisomers depends on the pattern substitution on the reactants.