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Paper | Regular issue | Vol 31, No. 8, 1990, pp.1439-1444
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5082
Pentacyclic Indole Alkaliods: A Short Synthesis of (±)-N(a)-Benzyl-20-desethylaspidospermidine

Daniel Gardette, Jean-Claude Gramain,* and Marie-Eve Sinibaldi

*Chimie des Substances Naturelles, URA 485 CNRS, Université Blaise Pascal (Clermont II), 63177 Aubière Cedex, France


The synthesis of (±)-N(a)-benzyl-20-desethylaspidospermidine in 8 steps and 25% overall yield from cyclohexanedione is described.