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Communication | Regular issue | Vol 29, No. 8, 1989, pp.1465-1468
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5052
Structure and Stereochemistry of Emargiatine-A, a Novel Cytotoxic Sesquiterpene Pyridine Alkaloid from Maytenus emarginata: X-Ray Crystal Steructure of Emarginatine-A Monohydrate

Yao-Haur Kuo, Chung-Hsiung Chen, Li-Ming Yang Kuo, Ming-Lu King, Tian-Shung Wu, Sheng-Teh Lu, Ih-Sheng Chen, Donald R. McPhail, Andrew T. McPhail,* and Kuo-Hsiung Lee*

*Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7360, U.S.A.


The structure and stereochemistry of emarginatine-A (1), a novel cytotoxic sesquiterpene pyridine alkaloid isolated from Maytenus emarginata, have been established from spectral data in conjunction with a single-crystal X-ray analysis of its monohydrate.