Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 29, No. 8, 1989, pp.1601-1605
Published online, 1st January, 1970
DOI: 10.3987/COM-89-5025
Convenient Preparations of 1,8-Dioxo-6-thioxopimerazino[1,2-c]perhydropyrimidines

Tadashi Ohkawara, Shigenori Matsumoto, Tetsuo Yamasaki,and Mitsuru Furukawa

*Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-hon-machi, Kumamoto 862-0973, Japan


Hydrolysis of 4-thiocarbamoyl-3-ethoxycarbonylmethylpiperazin-2-ones 3 in alkaline solution followed by acidification afforded 1,8-dioxo-6-thioxopiperazino[1,2-c]perhydropyrimidines 4 in 65-85% yields.