Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 29, No. 6, 1989, pp.1179-1183
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4943
Tris-N,N’,N"’-(3’,4’,5’-trimethoxyphenethyl)-1,3,5-hexahydrotriazine, a Methylenemescaline Trimer: Characterization and Selective Cyclization to Anhalinine under Non-aqueous Conditions

Linda A. Chrisey and Arnold Brossi

*Natural Products Research Center, Department of Chemistry, University of New Brunswick, Bag Service #45222, Fredericton, New Brunswick, E3b 5A3, Canada

Abstract

The product obtained from the reaction of mescaline with aqueous formaldehyde was assigned the hexahydrotriazine structure 3, on the basis of ms and 1H-nmr spectral data, and microanalysis. Reaction of 3 with hydrochloric acid in aqueous milieu afforded a mixture of anhalinine (2) and mescaline (1), however, exclusively 2 was obtained when the reaction was performed under non-aqueous conditions in glacial acetic acid or in dichloromethane with trifluoroacetic acid.