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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Paper | Regular issue | Vol 29, No. 6, 1989, pp.1097-1105
Published online, 1st January, 1970■ A One-pot Formation of the Analogues of Cherylline- and Latifine-type 4-Aryl-1,2,3,4-tetrahydroisoquinolines
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4889
■ A One-pot Formation of the Analogues of Cherylline- and Latifine-type 4-Aryl-1,2,3,4-tetrahydroisoquinolines
Masaru Kihara,* Seiichiro Iguchi, Yasuhiro Imakura, and Shigeru Kobayashi
*Pharmaceutical Sciences, Graduate of School, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan
Abstract
The cyclization reaction of N-(2-bromo-4,5-dimethoxybenzyl)-1-(4-methoxyphenyl) -2-aminoethanol (9) with conc. H2SO4, 80% H2SO4, or conc. HC1-benzene yielded cherylline analogues (5) and/or (6) along with latifine analogues (7) and/or (8) according to the biogenetic route.
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