Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 29, No. 6, 1989, pp.1097-1105
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4889
A One-pot Formation of the Analogues of Cherylline- and Latifine-type 4-Aryl-1,2,3,4-tetrahydroisoquinolines

Masaru Kihara,* Seiichiro Iguchi, Yasuhiro Imakura, and Shigeru Kobayashi

*Pharmaceutical Sciences, Graduate of School, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan


The cyclization reaction of N-(2-bromo-4,5-dimethoxybenzyl)-1-(4-methoxyphenyl) -2-aminoethanol (9) with conc. H2SO4, 80% H2SO4, or conc. HC1-benzene yielded cherylline analogues (5) and/or (6) along with latifine analogues (7) and/or (8) according to the biogenetic route.