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Communication | Regular issue | Vol 29, No. 4, 1989, pp.639-642
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4853
Enantioselective Total Syntheses of (4R,6R)-(+)-4-Hydroxy-6-pentylvalerolactone, ex Cephalosporium recifei, and of (6R)-(—)-Massoialactone

Frank Bennett, David W. Knight,* and Garry Fenton

*School of Chemistry, University of Nottingham, Nottingham NG7 2RD, U.K.


Total Syntheses of (4R,6R)-(+)-4-hydroxy-6-pentylvalerolactone (6) and (6R)-4-(-)-massoialactone (7) have been achieved, starting from the yeast reduction product methyl (3R)-3-hydroxyhexenoate (1).