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Paper | Regular issue | Vol 29, No. 6, 1989, pp.1065-1076
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4769
Fused Heterocyclic System. Note I. Pyrano[3,4-c]pyrrole-4,7(2H.6H)-dione. Synthesis and General Pharmacological Screening

Sergio Caronna, Liliana Lamartina, Salvatore Petruso, Vincenzo Spiro, Antonina Caruso, and Antonio Felice

*Tecnologie Farmaceutiche, Dipartimento di Chimica, Università digli Studi di Palermo, Via Archirafi 32, 90123 Palermo, Italy


A general synthesis of pyrano[3,4-c]pyrrole-4,7(2H,6H)-dione derivatives is described. The structures of epoxypropyl intermediates and of final compounds are demonstrated by 13C-nmr analysis. There are also reported the results of a general pharmacological screening on the compounds of the title.