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Paper | Regular issue | Vol 29, No. 2, 1989, pp.349-354
Published online, 1st January, 1970
DOI: 10.3987/COM-89-4758
Reactivity of Isoselenazoles towards Nucleophilic Reagents

Francesco Lucchesini, Nevio Picci, Marco Pocci, Angela De Munno,* and Vincenzo Bertini

*Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Via Risorgnimento 35, I-56126 Pisa, Italy


Isoselenazoles have shown two reactive sites towards nucleophiles. LDA gives metallation in the 5-position exploited for synthetic purposes. Grignard reagents and LAH attack the selenium atom forming non-cyclic functionalized systems.