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Communication | Regular issue | Vol 27, No. 9, 1988, pp.2091-2094
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4646
Synthesis of a New Skeleton, 2,6-Epithio-3-benzazocine

Mikio Hori,* Tadashi Kataoka, Hiroshi Shimizu, Eiji Imai, Noriyuki Iwata, Norihiro Kawamura, and Masayasu Kurono

*Department of Pharmacognosy, Gifu College of Pharmacy, 6-1 Mitahora-higashi 5-chome, Gifu 502-8585, Japan


Treatment of isothiochroman 2-oxide derivative (9) with acetic anhydride followed by heating in Dowtherm A (a mixture of biphenyl and diphenyl ether) afforded a novel 2,6-epithio-3-benzazocine derivative (2).