Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 27, No. 9, 1988, pp.2087-2090
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4644
1,3-Oxazolindid-5-ones, not 1,3-Diazetidinones, are Formed in the Reaction of Tryptophan with Alkyl Isocyanates in the Presence of Acetone

Alf Claesson*

*Research and Development Laboratories, Astra Alab, SE-151 85 Södertälja, Sweden

Abstract

A recent paper in This Journal by Braña et al. (Heterocycles 1987, 26, 95) reports isolation of 2-[(3-alkyl-4,4-dimethyl-2-oxo)-1,3-diazetidinyl]-3-(3-indolylpropionic acids from reactions of tryptophan with alkyl isocyanates in acetone. It appears most likely that these products are instead 1,3-oxazolidin-5-ones.