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Paper | Regular issue | Vol 27, No. 9, 1988, pp.2167-2174
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4592
Studies on the Constituents of Aconitum Species. VII. On the Components of Aconitum Japonicum Thunb

Hideo Bando, Koji Wada, Takashi Amiya,* Yasuo Fujimoto, and Kimiko Kobayashi

*Hokkaido College of Pharmacy, 7-1 Katsuraoka-cho, Otaru 047-02, Japan

Abstract

Two new diterpenoid alkaloids, subcumine (1) and subcusine (2), were isolated from the roots of Aconitum japonicum Thunb. The structures of these alkaloids were determined on the basis of spectral data, chemical evidence, and X-ray analysis. We also have isolated two known alkaloids, ezochasmaconitine (3) and anisoezochasmaconitine (4).