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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 27, No. 7, 1988, pp.1589-1593
Published online, 1st January, 1970■ Reaction of 3-Aclypyridinium Salts with Electrophilic Olefins. A One-pot Ring Annelation Reaction of Pyridines
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4564
■ Reaction of 3-Aclypyridinium Salts with Electrophilic Olefins. A One-pot Ring Annelation Reaction of Pyridines
Hans Bieräugel, Karel M. J. Brands, and Upendra K. Pandit*
*Laboratory of Organic Chemistry, Institute of Molecular Chemistry, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands
Abstract
The base-mediated addition of N-alkylated 3-pyridyl ketones (2a-d) to diethyl methylenemalonate (3) and ethyl α-phenylthioacrylate results in the formation of hexahydroisoquinoline derivatives in a one-pot reaction.
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