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Paper | Regular issue | Vol 27, No. 8, 1988, pp.1873-1879
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4547
Actinocinyl-bis(hemin); DNA-Intercalating Cleavage Agent

Yushin Nakamura*

*Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan

Abstract

The synthesis of actinocinyl-bis(mesoporphyrinatoiron) (1) was described. The intercalating bis(hemin) (1) caused effective DNA scission in the presence of Na2S2O4 under air.