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Paper | Regular issue | Vol 27, No. 9, 1988, pp.2133-2140
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4539
Biginelli Type Reaction with Tetroses Derivatives

M. Valpuesta Fernández,* F. J. López Herrera, and T. Lupión Cobos

*Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Málaga, Campus de Teations, E-29071 Malaga, Spain


The reaction of 2,4-0-ethylidene-D-erythrose and -threose with methyl acetoaoetate and urea, or thiourea, under the conditions of the Biginelli type reaction, gives as principal reaction products C-polyhydroxyalkylpyrimidines derivetives.