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Paper | Regular issue | Vol 27, No. 9, 1988, pp.2125-2131
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4535
Synthesis of Substituted Pyridines Using α,β-Unsaturated Nitriles and Active Cyano Compounds

Luis Fuentes,* Juan José Vaquero, Maria Isabel Ardid, Antonio Lerente, and José Luis Soto*

*Departamento de Química Orgánica, Universidad de Alcalá de Henares, 28871 Alcalá de Henares (Madrid), Spain


Several unknown 2-amino-substituted 3,4-dihydropyridines and pyridines are prepared by the reaction of α, β-unsaturated nitriles with active cyano compounds in the presence of a nucleophile reagent.