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Communication | Regular issue | Vol 27, No. 5, 1988, pp.1167-1168
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4525
A General Procedure for the Catalytic Hydrogenolysis of N-Benzylamines under Extremely Mild Conditions

Kiyoshi Yoshida,* Shigekazu Nakajima, Takeshi Wakamatsu, Yoshio Ban, and Masakatsu Shibasaki*

*Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan


A general procedure for debenzylation of N-benzylamines, which contain acid sensitive functional groups, by the catalytic hydrogenolysis using 20% Pd(OH)2-C is reported.