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Communication | Regular issue | Vol 27, No. 5, 1988, pp.1149-1154
Published online, 1st January, 1970
DOI: 10.3987/COM-88-4498
Four New Bisbenzylisoquinoline Alkaloids from the Root of Stephania Tetrandra (Fen-Fang Ji)

Tatsunori Ogino,* Toshitsugu Sato, Hiroshi Sasaki, Masao Chin (Chen Zhengxiong), and Hiroshi Mitsuhashi

*Kampo & Pharmacognosy Laboratory, Central Research Laboratory, Tsumura & Co., 3586 Yoshiwara, Ami-machi, Inashiki-gun, Ibaraki 300-1192, Japan

Abstract

Four new bisbenzylisoquinoline (BBI) alkaloids named fenfangjines A, B, C and D were isolated from the root of Stephania tetrandra S. Moore, the Chinese traditional medicine “Fen-Fang-Ji”, along with thirteen known alkaloids (1-13). The chemical structures of fenfangjines A, B, C and D were respectively determined to be (14),(15), (16) and (17) by spectral analyses and chemical methods.