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Paper | Regular issue | Vol 27, No. 4, 1988, pp.973-979
Published online, 1st January, 1970
DOI: 10.3987/COM-87-4455
Convenient Synthesis and Properties of Water Soluble Cyclodextrin Capped Mesoporphyrinatoiron

Takeshi Kato and Yushin Nakamura*

*Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan


The β-cyclodextrin-capped porphyrin was synthesized by a convenient procedure for a coupling reaction between diamino-β-cyclodextrin and mesoporphyrin dithiazolidine-2-thione in aqueous media. The thiazolidine compound was prepared by a condensation of mesoporphyrin and thiazolidine-2-thione in the presences of dicyclohexylcarbodiimide and N,N’-dimethylaminopyridine. The properties of the cyclodextrin capped heme were examined.