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Paper | Regular issue | Vol 27, No. 3, 1988, pp.725-732
Published online, 1st January, 1970
DOI: 10.3987/COM-87-4401
Isolation and Structural Studies on the Alkaloids of Alstonia macrophylla

Atta-ur-Rahman,* Muhammad Munawer Qureshi, Anjun Muzaffar, and Kuruneruge Tuley Dayanada de Silva*

*H. E. J. Postgraduate Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan


A new oxindole alkaloid, 16-hydroxy-Nb-demethylalstophylline oxindole (I) has been isolated from the leaves of Alstonia macrophylla. Its structure has been determined by modern spectroscopic studies, particularly by NOE difference, COSY 45° and DEPT enperiments. Na-Methyl-1,2-dihydrostrictamine (II) has also been isolated from this new source.