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Paper | Regular issue | Vol 27, No. 2, 1988, pp.437-444
Published online, 1st January, 1970
DOI: 10.3987/COM-87-4389
Synthesis of Argvalin and Its Related Compound

Akihiro Ohta,* Yutaka Aoyagi, Yohko Kurihara, Akihiko Kojima, Kayo Yuasa, and Makoto Shomazaki

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


Argvalin (3) and 6-(4-guanidinobutyl)-3-isobutyl-2(1H)-pyrazinone (4) were synthesized from DL-alanyl-valyl anhydride (6) and DL-alanyl-leucyl anhydride (5) respectively.