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Note | Special issue | Vol 73, No. 1, 2007, pp.857-862
Published online, 25th July, 2007
DOI: 10.3987/COM-07-S(U)18
Synthesis of Optically Pure 4-Hydroxymethyl-3-phenoxy-2-azetidinone from D-Glucal

Pilar Areces,* Esther Carrasco, Maria Monterde, Mark E. Light, and Joaquín Plumet*

*Department of Organic Chemistry, Faculty of Chemistry, University Complutense, 28040-Madrid, Spain

Abstract

A convenient approach to enantiomerically pure 4-hydroxymethyl- 3-phenoxy-2-azetidinone has been carried out using the easily available aldehyde 5 as chiral starting material.