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Note | Regular issue | Vol 75, No. 4, 2008, pp.955-963
Published online, 11th January, 2008
DOI: 10.3987/COM-07-11277
Synthesis and Reactions of Some New Spiro {Indeno[1,2-b]pyran-4,3’-indolines}

Maher F. El-Zohry,* Yasser A. Elossaily, Thanaa A. Mohamed, and Essam M. Hussein

*Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt


Indan-1,3-dione (1) reacted with 3-dicyanomethylidene-2-oxoindolines (2a-c) in refluxed ethanol to afford 2-amino-3-cyanospiro{5H-indeno[1,2-b] pyrane-4,3’-(1’-substitutedindoline)}-2’,5-diones (3a-c) which underwent different reactions to afford new spiro{indeno[2’,1’:5,6] pyrano[2,3-d]pyrimidine-5,3’-(1’-substitutedindoline)} (4a,b)-(12a,b) which are analogues of some reported biologically active spiropolycyclic compounds.