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Paper | Regular issue | Vol 75, No. 3, 2008, pp.619-634
Published online, 11th December, 2007
DOI: 10.3987/COM-07-11250
Synthesis of 4’-Thiopurine Nucleosides Using Hypervalent Iodine Compounds

Naozumi Nishizono,* Kayo Soma, Ryosuke Baba, Minoru Machida, and Kazuaki Oda*

*Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan

Abstract

The reaction of a silylated purine base with thiofuranoid using phenyl iodosyl bis(trifluoroacetate) gave 4’-thio purine nucleosides.