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Paper | Regular issue | Vol 75, No. 1, 2008, pp.131-143
Published online, 28th September, 2007
DOI: 10.3987/COM-07-11193
Megastigmane Glycosides from the Leaves of Salacia chinensis

Seikou Nakamura, Yi Zhang, Yutana Pongpiriyadacha, Tao Wang, Hisashi Matsuda, and Masayuki Yoshikawa*

*Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan


Six new megastigmane glycosides, foliasalaciosides A1 (1), A2 (2), B1 (3), B2 (4), C (5), and D (6), were isolated from the methanolic extract of the leaves of Salacia chinensis (Hippocrateaceae) collected in Thailand together with 16 known constituents. The absolute stereostructures of 1-6 were elucidated on the basis of chemical and physicochemical evidence including the application of the modified Mosher’s method.